Vertex Pharmaceuticals Incorporated

    VRTX ·NASDAQ ·Pharmaceutical Preparations ·Inc. in MA
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    1
    PART I
    ITEM 1.BUSINESS
    OVERVIEW
    We are a global biotechnology company that invests in scientific innovation to create transformative medicines for
    people with serious diseases, with a focus on specialty markets. We have approved medicines for cystic fibrosis (“CF”),
    sickle cell disease (“SCD”), transfusion dependent beta thalassemia (“TDT”), and acute pain, and we continue to serially
    innovate and advance next-generation clinical and research programs in these areas. Our mid- and late-stage clinical pipeline
    includes programs across a range of modalities in additional serious diseases, including IgA nephropathy, APOL1-mediated
    kidney disease, neuropathic pain, type 1 diabetes, primary membranous nephropathy, autosomal dominant polycystic kidney
    disease, and myotonic dystrophy type 1.
    The following chart sets forth our approved products, clinical-stage programs, and select pre-clinical programs:
    We are advancing five pivotal programs across multiple disease areas:
    IgA Nephropathy. We are developing povetacicept, a dual inhibitor of the B cell activating factor (“BAFF”) and a
    proliferation-inducing ligand (“APRIL”) pathways, as a potentially best-in-class approach to treat IgA nephropathy
    (“IgAN”), a serious, progressive, life-threatening kidney disease that often progresses to end-stage renal disease. We
    completed enrollment in the IgAN Phase 3 clinical trial and submitted the first module of the rolling Biologics
    Licensing Application (“BLA”) for povetacicept in IgAN in the fourth quarter of 2025. We expect to complete the
    submission for potential accelerated approval in the U.S. in the first half of 2026.
    APOL1-Mediated Kidney Disease. We are developing inaxaplin, a small molecule inhibitor of APOL1 as a potential
    first-in-class treatment for APOL1-mediated kidney disease (“AMKD”). We have completed the enrollment of the
    interim analysis cohort of the Phase 2/3 clinical trial and will conduct the pre-planned interim analysis once this
    cohort reaches 48 weeks of treatment. We expect to share data from the interim analysis in late 2026 or early 2027.
    Peripheral Neuropathic Pain. We are developing suzetrigine, a selective non-opioid NaV1.8 pain signal inhibitor,
    for diabetic peripheral neuropathy (“DPN”), a common form of peripheral neuropathic pain. We are evaluating
    suzetrigine for the treatment of DPN in two Phase 3 clinical trials. We expect to complete enrollment in both Phase
    3 clinical trials by the end of 2026.
    2
    Type 1 Diabetes. Zimislecel is an allogeneic stem-cell derived, fully differentiated islet cell therapy in pivotal
    development for the treatment of type 1 diabetes (“T1D”). We have completed enrollment in the Phase 1/2/3 clinical
    trial of zimislecel in people with T1D. We have temporarily postponed completion of the dosing in this clinical trial,
    pending an ongoing internal manufacturing analysis.
    Primary Membranous Nephropathy. We are also developing povetacicept to treat primary membranous nephropathy
    (“pMN”), a rare and serious autoimmune glomerular disease that can lead to kidney damage and renal failure, and
    which has no treatments specifically approved for this condition. We continue to enroll and dose patients in the
    adaptive Phase 2/3 pivotal trial in people with pMN. We expect to complete the Phase 2 portion of the clinical trial
    and to initiate the Phase 3 portion in mid-2026.
    Our core strategy is to discover, develop, and commercialize innovative medicines by combining transformative
    advances in the understanding of human disease and the science of therapeutics, to dramatically advance human health. We
    focus on validated targets that address causal human biology, predictive lab assays and clinical biomarkers, rapid paths to
    registration and approval, and product candidates that hold the potential for transformative patient benefit. Our approach
    includes advancing multiple compounds or therapies from each program into early clinical trials to obtain patient data that
    can inform selection of the most promising therapies for later stage development as well as inform our ongoing discovery and
    development efforts. We aim to serially innovate in our disease areas of interest and follow our first-in-class therapies with
    potential best-in-class candidates. We plan to continue investing to advance our strategy, fostering scientific innovation by
    identifying additional product candidates through internal research efforts, and investing in business development

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    Financial statements

    data from SEC XBRL filings. Values are as-reported; restatements supersede originals. Values reported in .

    From 10-Q filed 2026-08-04 (period ending 2026-06-30).

    Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations
    OVERVIEW
    We are a global biotechnology company that invests in scientific innovation to create transformative medicines for
    people with serious diseases, with a focus on specialty markets. We have seven approved medicines: five that treat the
    underlying cause of cystic fibrosis (“CF”), a life-threatening genetic disease, one that treats severe sickle cell disease
    (“SCD”) and transfusion dependent beta thalassemia (“TDT”), life shortening inherited blood disorders, and one that treats
    moderate-to-severe acute pain. We are also preparing for the anticipated launch of povetacicept, a potential treatment for IgA
    nephropathy (“IgAN”). Our clinical-stage pipeline spans a range of programs targeting CF, SCD, beta thalassemia,
    neuropathic pain, type 1 diabetes, IgA nephropathy, primary membranous nephropathy and other autoimmune diseases and
    cytopenias, APOL1-mediated kidney disease, autosomal dominant polycystic kidney disease and myotonic dystrophy type 1,
    reflecting our commitment to addressing significant unmet medical needs globally.
    Financial Highlights
    Total Revenues
    In the second quarter of 2026, our total revenues increased to $3.3 billion as compared to $3.0
    billion in the second quarter of 2025, primarily due to continued performance of our CF therapies
    and growth from diversification into additional disease areas.
    Cost of Sales
    Our cost of sales as a percentage of our net product revenues increased to 14.7% in the second
    quarter of 2026 as compared to 13.8% in the second quarter of 2025, as a result of changes in
    product mix, partially offset by a lower blended royalty rate for our CF medicines.
    Total R&D, AIPR&D
    and SG&A Expenses
    Our total research and development (“R&D”), acquired in-process research and development
    expenses (“AIPR&D”) and selling, general and administrative (“SG&A”) expenses increased to
    $1.6 billion in the second quarter of 2026 as compared to $1.4 billion in the second quarter of
    2025, primarily due to increased investment to commercialize our new products.
    Cash
    Our total cash, cash equivalents and marketable securities increased to $13.6 billion as of June 30,
    2026 as compared to $12.3 billion as of December 31, 2025 primarily due to cash flows provided
    by our operating activities, partially offset by repurchases of our common stock.
    Q2 2025
    Q2 2026
    December 31, 2025
    June 30, 2026
    Note: Charts above may not add due to rounding.
    Business Updates
    Marketed Products
    Cystic Fibrosis
    We expect that the number of people with CF taking our medicines will continue to grow through new approvals and
    reimbursement agreements, treatment of younger patients, increased survival and expansion into additional geographies.
    Recent progress in activities expanding our CF business is included below:
    In the second quarter of 2026, we secured reimbursement for ALYFTREK in four additional countries, including
    Spain, bringing the total number of countries where ALYFTREK is reimbursed to 25. We also signed a letter of
    intent with the Pan-Canadian Pharmaceutical Alliance for reimbursement of ALYFTREK for eligible patients six
    years of age and older in Canada.
    23
    Sickle Cell Disease and Beta Thalassemia
    In the second quarter of 2026, we recorded $76.4 million of CASGEVY product revenues, representing a 78%
    increase compared to the first quarter of 2026 and a 151% increase compared to the second quarter of 2025.
    The U.S. Food and Drug Administration (the “FDA”) approved CASGEVY in children two years of age and older
    with SCD or TDT, making it the first genetic therapy indicated for children as young as two years of age for both
    SCD and TDT. Approximately 5,500 patients with SCD or TDT may be eligible for treatment with CASGEVY for
    the first time with this approval. We also completed regulatory submissions in the Kingdom of Saudi Arabia (“Saudi
    Arabia”) and the United Kingdom for the treatment of children five to eleven years of age.
    In May, we secured reimbursement for CASGEVY for eligible patients 12 years and older with SCD or TDT in
    Germany. We are committed to working with government and reimbursement authorities globally to ensure
    sustainable access for eligible patients.
    Acute Pain
    In the second quarter of 2026, we recorded $49.6 million of JOURNAVX product revenues, representing a 71%
    increase compared to the first quarter of 2026 and a more than 300% increase compared to the second quarter of
    2025.
    In the second quarter and first six months of 2026, approximately 535,000 and 900,000 prescriptions, respectively,
    have been filled for JOURNAVX across the hospital and retail settings.
    We have reached agreements with two additional major pharmacy benefit managers for Medicare Part D coverage of
    JOURNAVX. As a result, seniors covered by three of the four major Medicare Part D pharmacy benefit managers
    have reimbursed access. Twenty-three states provide coverage for JOURNAVX via Medicaid. In total,
    approximately 260 million individuals have reimbursed access to JOURNAVX across a wide range of commercial
    and government payers.
    Pipeline
    We continue to advance a diversified pipeline of potentially transformative medicines for serious diseases utilizing a
    range of modalities. Recent and anticipated progress in activities supporting these efforts is included below:
    Cystic Fibrosis
    Following positive results from the Phase 3 clinical trial evaluating ALYFTREK in children with CF two to five
    years of age, we initiated global regulatory submissions for this age group.
    Acute and Peripheral Neuropathic Pain
    During the second quarter of 2026, Health Canada accepted our new drug submission for suzetrigine for the
    treatment of moderate-to-severe acute pain, and review is underway.
    We expect to complete enrollment in both Phase 3 clinical trials evaluating suzetrigine in diabetic peripheral
    neuropathy, a form of peripheral neuropathic pain, by the end of 2026.
    IgA Nephropathy and Other B Cell-Mediated Diseases
    We are developing povetacicept, a dual inhibitor of B cell activating factor (“BAFF”) and a proliferation-inducing
    ligand (“APRIL”) cytokines, for multiple diseases. Povetacicept represents a potentially best-in-class approach to
    control B cell activity in IgAN.
    The FDA accepted our biologics license application for accelerated approval of povetacicept for adults with IgAN
    and assigned a PDUFA target action date of November 30, 2026. If approved, povetacicept will become the first
    commercialized therapy in our emerging nephrology franchise.
    We have completed our regulatory submission for accelerated approval of povetacicept in adults with IgAN in Saudi
    Arabia, and the Saudi Food and Drug Authority has granted Breakthrough Designation to povetacicept.
    Povetacicept represents a potentially best-in-class approach to control B cell activity in primary membranous
    nephropathy (“pMN”), another B cell-mediated disease. We completed the Phase 2B portion of the Phase 2/3
    24
    OLYMPUS pivotal trial evaluating povetacicept in people with pMN, and we confirmed the dose selection for the
    Phase 3 portion, which is underway.
    APOL1-Mediated Kidney Disease
    Inaxaplin is our small molecule for the treatment of APOL1-mediated kidney disease (“AMKD”). We expect to
    complete full enrollment in the AMPLITUDE Phase 2/3 pivotal clinical trial evaluating inaxaplin in the second half
    of 2026.
    We expect to share data from the interim analysis of the AMPLITUDE clinical trial in early 2027. We expect to
    conduct the pre-planned interim analysis for potential U.S. accelerated approval once the interim analysis cohort has
    been treated for 48 weeks.
    Type 1 Diabetes
    Zimislecel is an allogeneic, stem cell-derived, fully differentiated, insulin-producing islet cell replacement therapy,
    using standard immunosuppression to protect the implanted cells. We are enrolling and dosing patients in the Phase
    1/2/3 clinical trial of zimislecel in people with type 1 diabetes (“T1D”).
    The FDA cleared the Investigational New Drug Application for VX-017, our stem cell-derived, fully differentiated
    islet cell therapy designed to treat all eligible patients with T1D, regardless of blood type. We plan to initiate a Phase
    1/2 clinical trial to evaluate the safety and efficacy of VX-017 in people with T1D in the near term.
    We expect to provide updated timelines for the zimislecel and VX-017 programs in 2026.
    Investment in External Innovation
    In July, we entered into an agreement and plan of merger (the “Crinetics Merger Agreement”) to acquire all of the
    issued and outstanding shares of common stock of Crinetics Pharmaceuticals, Inc. (“Crinetics”) for $85.00 per share
    in cash, for a total equity value of approximately $10.0 billion (the “Crinetics Acquisition”). We expect the
    transaction to close in the third quarter of 2026, subject to certain customary conditions. Crinetics’ PALSONIFY®
    (paltusotine) is a once-daily oral therapy for adults with acromegaly, a rare and debilitating condition caused by a
    pituitary tumor that secretes excess growth hormone, who had an inadequate response to surgery and/or for whom
    surgery is not an option. PALSONIFY is approved by the FDA and the European Medicines Agency, and is under
    review by other global regulatory bodies. Crinetics’ most advanced pipeline candidate, atumelnant, is a once-daily
    oral adrenocorticotropic hormone receptor antagonist in Phase 3 development for congenital adrenal hyperplasia.
    Our Business Environment
    In the first half of 2026, our total product revenues came primarily from the sale of our medicines for the treatment of
    CF. Our CF strategy involves continuing to develop and obtain approval and reimbursement for treatment regimens that will
    provide benefits to all people with CF and increasing the number of people with CF eligible and able to receive our
    medicines. Outside of CF, we continue to advance the commercialization of CASGEVY for the treatment of SCD and TDT,
    and JOURNAVX for the treatment of acute pain, and we are preparing for a potential launch of povetacicept for the treatment
    of IgAN. In addition, we are advancing our pipeline of product candidates for the treatment of serious diseases outside of CF,
    SCD, TDT and acute pain.
    Our strategy is to combine transformative advances in the understanding of causal human biology and the science of
    therapeutics to discover and develop innovative medicines. This approach includes advancing multiple compounds or
    therapies from each program, spanning multiple modalities, into early clinical trials to obtain patient data that can inform
    selection of the most promising therapies for later-stage development, as well as to inform discovery and development
    efforts. We aim to serially innovate in our disease areas of interest and follow our first-in-class therapies with potential best-
    in-class candidates to provide durable clinical and commercial success.
    In pursuit of new product candidates and therapies in specialty markets, we invest in research and development. We
    believe that pursuing research in diverse areas allows us to balance the risks inherent in product development and may
    provide product candidates that will form our pipeline in future years. To supplement our internal research programs, we
    acquire technologies and programs and collaborate with biopharmaceutical and technology companies, leading academic
    research institutions, government laboratories, foundations and other organizations, as needed, to advance research in our
    areas of therapeutic interest and to access technologies needed to execute on our strategy.
    25
    Discovery and development of a new pharmaceutical or biological product is a difficult and lengthy process that requires
    significant financial resources along with extensive technical and regulatory expertise. Across the industry, most potential
    drug or biological products never progress into development, and most products that advance into development never receive
    marketing approval. Our investments in product candidates are subject to considerable risks. We closely monitor our research
    and development activities, and frequently evaluate our pipeline programs in light of new data and scientific, business and
    commercial insights, with the objective of balancing risk and potential. This process can result in rapid changes in focus and
    priorities as new information becomes available and as we gain additional understanding of our ongoing programs and
    potential new programs, as well as those of our competitors. In addition, our product candidates must satisfy rigorous
    standards of safety and efficacy before they can be approved for sale by regulatory authorities. Our analysis of data obtained
    from nonclinical and clinical activities is subject to confirmation and interpretation by regulatory authorities, which could
    delay, limit or prevent regulatory approval.
    Our business also requires ensuring appropriate manufacturing and supply of our products. As we advance our product
    candidates through clinical development toward commercialization and market and sell our approved products, we build and
    maintain our supply chain and quality assurance resources. We rely on a global network of third parties, including some in
    China, and our internal capabilities to manufacture and distribute our products for commercial sale and post-approval clinical
    trials and to manufacture and distribute our product candidates for clinical trials. In addition to establishing supply chains for
    each newly approved product, we adapt our supply chain for existing products to include additional formulations or to
    increase scale of production for existing products as needed. The processes for biological and cell and genetic therapies can
    be more complex than those required for small molecule drugs and require additional investments in different systems,
    equipment, facilities and expertise. We are focused on ensuring the stability of the supply chains for our current products, as
    well as for our pipeline programs.
    Sales of our products depend, to a large degree, on the extent to which our products are reimbursed by third-party payors,
    such as government health programs, commercial insurance and managed health care organizations. Reimbursement for our
    products, including our potential pipeline therapies, cannot be assured and may take significant periods of time to obtain. We
    dedicate substantial management and other resources to obtain and maintain appropriate levels of reimbursement for our
    products from third-party payors, including governmental organizations in the U.S. and ex-U.S. markets. In the U.S., we
    work with government and commercial payors to obtain and maintain appropriate levels of reimbursement for our medicines.
    In ex-U.S. markets, we seek government reimbursement for our medicines on a country-by-country or region-by-region, as
    required. This is necessary for each new medicine, as well as for label expansions for our current medicines. We expect to
    continue to focus significant resources to expand and maintain reimbursement for our CF medicines, CASGEVY,
    JOURNAVX, and, ultimately, our pipeline therapies, in U.S. and ex-U.S. markets.
    Strategic Transactions
    Acquisitions
    As part of our business strategy, we seek to license or acquire technologies, products, product candidates and businesses
    that are aligned with our corporate and research and development strategies and complement and advance our ongoing
    research and development efforts. We have acquired multiple biotechnology companies over the last several years and expect
    to continue to identify and evaluate such opportunities. The accounting for an acquisition can vary significantly based on
    whether we conclude the relevant transaction represents a business combination or asset acquisition.
    In 2024, we acquired Alpine Immune Sciences, Inc. (“Alpine”) and its lead molecule, povetacicept, for approximately
    $5.0 billion. Povetacicept, has shown potential to treat multiple diseases or conditions and become a pipeline-in-a-product.
    We accounted for the Alpine transaction as an asset acquisition because povetacicept represented substantially all of the fair
    value of the gross assets that we acquired. As a result, $4.4 billion of the fair value attributed to povetacicept was expensed as
    AIPR&D in 2024.
    In July 2026, we entered into the Crinetics Merger Agreement to acquire Crinetics as described above. Crinetics is a
    publicly traded biotechnology company focused on discovering, developing, and commercializing novel therapeutics for
    endocrine diseases and endocrine-related tumors. We will acquire Crinetics for $85.00 per share in cash, for a total equity
    value of approximately $10.0 billion. We expect to fund the acquisition with our cash, cash equivalents, and proceeds from
    the 2026 Term Loan, as defined below. The Crinetics Acquisition is not conditioned on our receipt of financing. We will
    account for the acquisition in the period that it closes.
    26
    Collaboration and In-Licensing Arrangements
    We enter into arrangements with third parties, including collaboration and licensing arrangements, for the development,
    manufacture and commercialization of products, product candidates and other technologies that have the potential to
    complement our ongoing research and development efforts.
    Over the last several years, we entered into collaboration agreements with a number of companies, including CRISPR
    Therapeutics AG (“CRISPR”) and Entrada Therapeutics, Inc. (“Entrada”).
    Generally, when we in-license a technology or product candidate, we make upfront payments to the collaborator, assume
    the costs of the program and/or agree to make contingent payments, which could consist of milestone, royalty and option
    payments. Most of these collaboration payments are expensed as AIPR&D because they were primarily attributable to
    acquired in-process research and development for which there was no alternative future use. However, depending on many
    factors, including the structure of the collaboration, the stage of development of the acquired technology, the significance of
    the in-licensed product candidate to the collaborator’s operations and the other activities in which our collaborators are
    engaged, the accounting for these transactions can vary significantly. We expect to continue to identify and evaluate
    collaboration and licensing opportunities that may be similar to or different from the collaborations and licenses that we have
    engaged in previously.
    Acquired In-Process Research and Development Expenses
    In the first half of 2026 and 2025, our AIPR&D included $21.9 million and $22.0 million, respectively, related to
    upfront, contingent milestone, or other payments pursuant to our business development transactions, including the asset
    acquisitions, collaborations, and licenses of third-party technologies described above. Please refer to Note B, “Collaboration,
    License and Other Arrangements,” for further information regarding our asset acquisitions, collaborations and in-license
    agreements.
    Out-licensing Arrangements
    We also have out-licensed certain development programs to collaborators who are leading the development or
    commercialization of these programs, either globally or within certain geographic regions.
    In January 2025 and June 2025, we entered into agreements with Zai Lab Limited (“Zai”) and Ono Pharmaceuticals Co.,
    Ltd (“Ono”), respectively, for the development and commercialization of povetacicept in various Asian markets. Zai licensed
    povetacicept for mainland China, Hong Kong SAR, Macau SAR, Taiwan region and Singapore, while Ono licensed
    povetacicept for Japan and South Korea. Zai and Ono will help advance povetacicept clinical trials, and will be responsible
    for obtaining marketing authorizations and commercialization activities, if povetacicept becomes an approved product, in
    their licensed territories. We are eligible to receive certain future milestone payments and tiered royalties on future net sales
    of povetacicept in these regions.
    27
    RESULTS OF OPERATIONS
    Total Revenues
    Three Months Ended
    June 30,
    Six Months Ended
    June 30,
    2026
    2025
    Change
    2026
    2025
    Change
    (in millions, except percentages)
    TRIKAFTA/KAFTRIO
    $2,497.2
    $2,551.1
    (2)%
    $4,851.9
    $5,086.6
    (5)%
    ALYFTREK
    573.6
    156.8
    266%
    998.0
    210.7
    374%
    Other CF product revenues (1)
    137.1
    193.7
    (29)%
    273.0
    349.0
    (22)%
    Total CF product revenues, net
    3,207.9
    2,901.6
    11%
    6,122.9
    5,646.3
    8%
    CASGEVY
    76.4
    30.4
    151%
    119.3
    44.6
    167%
    JOURNAVX
    49.6
    12.0
    313%
    78.6
    13.3
    491%
    Product revenues, net
    3,333.9
    2,944.0
    13%
    6,320.8
    5,704.2
    11%
    Other revenues
    20.7
    **
    30.7
    **
    Total revenues
    $3,333.9
    $2,964.7
    12%
    $6,320.8
    $5,734.9
    10%
    (1) Include KALYDECO, ORKAMBI and SYMDEKO/SYMKEVI.
    ** Not meaningful
    Product Revenues, Net
    In the second quarter and first half of 2026, our net product revenues increased 13% and 11%, as compared to the second
    quarter and first half of 2025, respectively, primarily due to continued performance of our CF therapies and growth from
    diversification into additional disease areas.
    Other Revenues
    In the second quarter of 2025, our other revenues included a $20.6 million upfront payment received from our
    collaboration agreement with Ono Pharmaceuticals Co., Ltd. In the first half of 2025, our other revenues also included a
    $10.0 million upfront payment received from our collaboration agreement with Zai Lab Limited.
    Total Revenues by Geographic Location
    Our total revenues from the U.S. and from ex-U.S. markets were as follows:
    Three Months Ended
    June 30,
    Six Months Ended
    June 30,
    2026
    2025
    Change
    2026
    2025
    Change
    (in millions, except percentages)
    United States
    $2,056.4
    $1,848.2
    11%
    $3,832.3
    $3,511.7
    9%
    ex-U.S.
    1,277.5
    1,116.5
    14%
    2,488.5
    2,223.2
    12%
    Total revenues
    $3,333.9
    $2,964.7
    12%
    $6,320.8
    $5,734.9
    10%
    In the second quarter and first half of 2026, our U.S. total revenues increased 11% and 9%, as compared to the second
    quarter and first half of 2025, respectively, primarily due to continued strong patient demand, including from new initiations
    of ALYFTREK, and higher realized net prices in CF, and contributions from CASGEVY and JOURNAVX.
    In the second quarter and first half of 2026, our ex-U.S. total revenues increased 14% and 12%, as compared to the
    second quarter and first half of 2025, respectively, primarily due to strong CF performance across multiple geographies,
    including ALYFTREK uptake, increased CASGEVY product revenues, and favorable impacts from foreign exchange.
    28
    Operating Costs and Expenses

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    Held by

    holders ( registered funds via N-PORT, institutional investors via 13F). Showing top by dollar value.

    Holder Type ETF MF Position ($) % of holder Δ % of holder Holder AUM

    Recent insider activity

    Last 90 days. Open-market trades (purchases & sales) by directors, officers, and 10%+ owners. 9 transactions across 4 insiders. Net: -14,094 shares, -$6,628,187.

    Date Insider Role Action Shares Price Value
    2026-07-02 Tatsis Ourania EVP, Chief Reg. & Quality Off. Sell -1,500 $524.99 -$787,485
    2026-07-02 McKechnie Duncan EVP, Chief Commercial Officer Sell -1,541 $519.00 -$799,779
    2026-07-01 Liu Joy EVP and Chief Legal Officer Sell -828 $502.71 -$416,244
    2026-06-26 Bozic Carmen EVP and CMO Sell -596 $482.50 -$287,570
    2026-06-18 Bozic Carmen EVP and CMO Sell -1,020 $462.17 -$471,413
    2026-06-15 Bozic Carmen EVP and CMO Sell -4,062 $450.00 -$1,827,900
    2026-06-05 Bozic Carmen EVP and CMO Sell -1,745 $450.00 -$785,250
    2026-06-01 Liu Joy EVP and Chief Legal Officer Sell -828 $439.91 -$364,245
    2026-05-29 Bozic Carmen EVP and CMO Sell -1,974 $450.00 -$888,300

    Source: SEC Form 4 filings.

    Next expected filings

    • ~2026-11-03 10-Q expected by 2026-11-08 (in 72 days)
    • ~2027-02-13 10-K expected by 2027-03-05 (in 174 days)
    • ~2027-05-04 10-Q expected by 2027-05-09 (in 254 days)
    • ~2027-08-03 10-Q expected by 2027-08-08 (in 345 days)

    Predicted from historical filing cadence; not an SEC commitment.

    Recent SEC filings

    • 2026-08-04 10-Q Quarterly Report
    • 2026-08-03 8-K Earnings Release; Financial Statements and Exhibits
    • 2026-07-07 8-K Material Agreement Entered; Regulation FD Disclosure; Other Events; Financial Statements and Exhibits
    • 2026-05-13 8-K Officer/Director Change; Shareholder Vote Results
    • 2026-05-13 S-8 Employee Benefit Plan Registration
    • 2026-05-05 10-Q Quarterly Report
    • 2026-05-04 8-K Earnings Release; Financial Statements and Exhibits
    • 2026-04-29 8-K Officer/Director Change
    • 2026-03-31 8-K Other Events
    • 2026-02-13 10-K Annual Report
    • 2026-02-12 8-K Earnings Release; Financial Statements and Exhibits
    • 2025-11-04 10-Q Quarterly Report
    • 2025-11-03 8-K Earnings Release; Financial Statements and Exhibits
    • 2025-08-05 10-Q Quarterly Report
    • 2025-08-04 8-K Earnings Release; Officer/Director Change; Financial Statements and Exhibits