State Street SPDR S&P Biotech

    XBI ·NYSEARCA
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    The State Street SPDR S&P Biotech ETF (the “Fund”) seeks to provide investment results that, before fees

    Investment Strategy

    In seeking to track the performance of the S&P Biotechnology Select Industry Index (the “Index”), the Fund employs a sampling strategy, which means that the Fund is not required to purchase all of the securities represented in the Index. Instead, the Fund may purchase a subset of the securities in the Index in an effort to hold a portfolio of securities with generally the same risk and return characteristics of the Index. The quantity of holdings in the Fund will be based on a number of factors, including asset size of the Fund. Based on its analysis of these factors, SSGA Funds Management, Inc. (“SSGA FM” or the “Adviser”), the investment adviser to the Fund, either may invest the Fund's assets in a subset of securities in the Index or may invest the Fund's assets in substantially all of the securities represented in the Index in approximately the same proportions as the Index, as determined by the Adviser to be in the best interest of the Fund in pursuing its objective.

    Fees & Expenses

    Net Expense Ratio0.35%
    Management Fee0.35%
    Portfolio Turnover43%

    Reported Performance

    Average annual returns as reported in the fund's most recent prospectus. Past performance does not guarantee future results.

    1-Year Return1.10%
    5-Year Avg Annual1.02%
    10-Year Avg Annual3.97%

    Holdings

    158 positions as of 2026-03-31. Total net assets: $7,434,448,909. Expense ratio: 0.35%. Source: SEC N-PORT-P filing.

    Top 10 holdings

    Name Ticker Weight Value
    State Street Navigator Securities Lending Portfolio II GVMXX 8.01% $595,460,501
    Apellis Pharmaceuticals Inc APLS 1.83% $136,397,964
    Alkermes PLC ALKS 1.45% $107,877,349
    Madrigal Pharmaceuticals Inc MDGL 1.38% $102,813,696
    TG Therapeutics Inc TGTX 1.35% $100,334,399
    Insmed Inc INSM 1.34% $99,394,814
    Scholar Rock Holding Corp SRRK 1.30% $96,450,199
    Apogee Therapeutics Inc APGE 1.28% $95,481,943
    Protagonist Therapeutics Inc PTGX 1.24% $92,548,683
    Summit Therapeutics Inc SMMT 1.24% $92,267,854

    Country

    CountryWeight
    United States 103.3%
    Ireland 1.6%
    Switzerland 1.1%
    Bermuda 1.1%
    British Virgin Islands 0.4%
    Netherlands 0.4%
    Canada 0.1%
    Total 108.0%

    Region

    RegionWeight
    Americas 105.0%
    Europe 3.0%
    Total 108.0%

    Market classification

    MarketWeight
    Developed 106.5%
    Other 1.5%
    Total 108.0%

    Sector

    SectorWeight
    Health Care 98.3%
    Industrials 1.3%
    Financials 0.2%
    Unknown 8.2%
    Total 108.0%

    Market cap

    CapWeight
    Mega 1.1%
    Large 10.3%
    Mid 16.1%
    Small 26.7%
    Micro 45.5%
    Non-equity 8.2%
    Total 108.0%

    Asset class

    ClassWeight
    Equity-common 99.8%
    Short-term investment 8.1%
    Derivative-equity 0.2%
    Total 108.0%

    Issuer type

    TypeWeight
    Corporate 99.8%
    Registered fund 8.1%
    Unknown 0.2%
    Total 108.0%

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    Held by

    holders ( registered funds via N-PORT, institutional investors via 13F). Showing top by dollar value.

    Holder Type ETF MF Position ($) % of holder Δ % of holder Holder AUM