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CRISPR-Edited ‘Off-the-Shelf’ CAR-T Cells Show Early Promise Against Recurrent Glioblastoma in Small China Trial

In a five-patient phase 1 study, intrathecal CRISPR-edited donor CAR-T cells appeared safe and shrank recurrent high-grade gliomas.

#glioblastoma, #cart, #crispr, #immunotherapy, #clinicaltrials