Tag: #cardiology

Sham-controlled trial finds pulmonary vein isolation no better than sham for atrial fibrillation quality of life at six months

A multicentre sham-controlled trial in Europe published in The Lancet found PVI didn’t improve AF-related quality of life versus sham at six months.

#atrialfibrillation, #catheterablation, #cardiology, #clinicaltrials

Phase 1 study: single dose of Kylo-11 sharply lowers Lp(a) for up to 48 weeks

A phase 1 trial in The Lancet found one dose of experimental siRNA Kylo-11 was well tolerated and cut Lp(a) by up to ~98% for months.

#lpa, #cardiology, #drugdevelopment, #sirna

One-month dual antithrombotic strategy after PCI reduced bleeding without higher 12‑month thromboembolic risk in OPTIMA‑AF trial

OPTIMA‑AF found that stopping dual antithrombotic therapy after one month and continuing a DOAC alone reduced bleeding without raising 12‑month death or thromboembolism.

#cardiology, #atrialfibrillation, #pci, #anticoagulation

Eugene Braunwald, Pioneering Cardiologist, Dies at 96

Eugene Braunwald, a trailblazer in cardiology whose research and textbooks reshaped heart care, died April 22 at 96 in Massachusetts.

#cardiology, #obituary, #medicine, #research