Tag: #clinicaltrials

Pfizer’s Phase 3 Lung Cancer Drug Misses Overall Survival Goal; Stronger Trend in Second‑Line Patients

Pfizer's Phase 3 lung cancer trial of sigvotatug vedotin missed its overall survival goal; company sees a stronger trend in second‑line patients.

$PFE, #pfizer, #oncology, #lungcancer, #clinicaltrials

UK Phase I trial finds AI-designed coronavirus vaccine candidate safe and elicits cross-reactive immune responses

Phase I UK trial: an AI-designed DNA vaccine for sarbecoviruses was safe in 39 adults and induced cross-reactive immune responses, but not proof it protects.

#covid-19, #vaccine, #clinicaltrials, #ai

Interim phase 3: Sacituzumab tirumotecan plus pembrolizumab improves PFS in PD-L1–positive advanced NSCLC

Interim phase 3 data: adding sacituzumab tirumotecan to pembrolizumab improved progression-free survival versus pembrolizumab alone in PD‑L1+ advanced NSCLC; OS immature, toxicity higher.

$MRK, #lungcancer, #pembrolizumab, #sacituzumabtirumotecan, #clinicaltrials