Tag: #cancer

FDA Grants Accelerated Approval for GSK’s Jemperli in Biomarker-Defined Locally Advanced Rectal Cancer

FDA grants accelerated approval to GSK’s Jemperli for adults with stage II–III dMMR/MSI‑H locally advanced rectal cancer, potentially avoiding surgery.

$GSK, #health, #cancer, #fda, #immunotherapy

Study identifies backup pathway that lets cells make cysteine without major disulfide reductases

Researchers report a PLP-dependent cystine C–S bond cleavage in mouse livers that supplies cysteine even when main disulfide reductases are absent.

#cellbiology, #cysteine, #metabolism, #cancer

NHS-Galleri Trial Misses Primary Endpoint; Secondary Analysis Shows Fewer Stage IV Cancers

A large randomized NHS trial of Grail’s Galleri multi-cancer blood test missed its primary endpoint, though secondary analysis found fewer Stage IV cancers.

#cancer, #screening, #galleri, #clinicaltrials

NHS begins rolling out free at-home HPV self-test kits to nearly 4 million overdue for cervical screening

NHS England is inviting nearly 4 million people overdue for cervical screening to order free at-home HPV self-test kits to boost uptake and prevent cancer.

#nhs, #hpv, #cervicalscreening, #publichealth, #cancer

Pirtobrutinib Triplet Prolongs Progression-Free Survival in Previously Treated CLL, Lancet Reports

Phase 3 BRUIN CLL-322 found fixed-duration pirtobrutinib with venetoclax–rituximab cut progression/death risk by ~45% vs venetoclax–rituximab in relapsed CLL.

$LLY, #cancer, #cll, #hematology, #pirtobrutinib

WHO Projects Global Cancer Cases Could Reach Nearly 35 Million by 2050, Warns of Growing Inequities

WHO projects new cancer cases from 20.6M (2024) to nearly 35M by 2050, warning low-income countries will bear the heaviest burden without stronger prevention.

#cancer, #who, #globalhealth, #publichealth

NHS England rolls out 60-second pembrolizumab injection to cut treatment chair time

NHS England is introducing a subcutaneous form of pembrolizumab (Keytruda) that can be given in about a minute, reducing clinic time for roughly 14,000 patients.

#nhs, #pembrolizumab, #cancer, #immunotherapy

Brazil's new cancer framework promises free advanced therapies through SUS and a push for domestic production

Brazil approved a framework to expand free access to advanced cancer therapies via SUS, speed regulatory reviews and favor domestic production.

#brazil, #healthcare, #cancer, #anvisa