Tag: #crispr

Engineered miniature CRISPR achieves >80% editing in human cells and could fit inside AAV

Engineered miniature CRISPR raised editing in human cells from <10% to >80% and stays small enough to fit in AAV vectors — tests remain in cells.

#gene-editing, #crispr, #aav, #biotechnology

FDA proposes new pathway to approve one-patient gene-editing drugs for ultra-rare diseases

New FDA draft guidance would let individualized CRISPR and RNA therapies win approval with tiny studies, using strong biology and natural-history data.

#fda, #geneediting, #raredisease, #crispr, #drugapproval

Engineered CRISPR plasmid spreads through bacteria to erase antibiotic resistance — with an added off switch

UC San Diego scientists report a self-propagating CRISPR plasmid that moves through bacterial communities, deletes a resistance gene and can be reversed.

#crispr, #antibioticresistance, #microbiology, #biofilms, #genedrive