Science & Tech

Engineered ‘living’ cell implant normalizes blood pressure in mice, study shows

Engineered human cell implants sense angiotensin II and secrete soluble ACE2 to restore normal blood pressure in hypertensive mice.

#syntheticbiology, #hypertension, #genetherapy, #ace2

Pol32 phosphorylation strengthens RPA binding and promotes mutagenic break‑induced replication in yeast

Study in budding yeast finds phosphorylation of two threonines in Pol32 strengthens its binding to RPA and promotes mutagenic break‑induced replication.

#dna-repair, #bir, #pol32, #yeast

23andMe study finds common gene variants modestly affect weight loss and nausea on GLP‑1 drugs

A Nature paper by 23andMe links common DNA variants to small differences in weight loss and nausea on GLP‑1 drugs; the company released a consumer report.

#genetics, #glp1, #23andme, #weightloss, #semaglutide

Study projects nearly 2.6 billion people could face frequent ‘hot‑dry’ heat-and-drought extremes by 2090s

A new study finds that under current trajectories about 28% of humanity—nearly 2.6 billion people—could face frequent simultaneous heat and drought by the 2090s.

#climate, #heat, #drought, #adaptation

NASA Begins Scrutinizing Artemis II’s Lunar Flyby Data as Orion Heads Home

After Artemis II's lunar flyby, NASA is analyzing 50+ GB of images, audio and measurements — including meteoroid flashes and far‑side imagery — as Orion returns.

#space, #nasa, #artemis, #moon

NIH Spotlights Women's Health and BRAIN Tech Partnerships — No New Funding Announced

NIH's April 7 meetings emphasized maternal health, equity and disseminating BRAIN technologies — but released no new funding or formal policy changes.

#nih, #womenshealth, #braininitiative, #researchfunding

Glial relay in hypothalamus links blood sugar to appetite suppression

Rodent study reveals a glia‑to‑glia‑to‑neuron circuit: tanycytes release lactate, activating astrocytes that excite appetite‑suppressing POMC neurons.

#neuroscience, #appetite, #glia, #hypothalamus

NOAA‑20 Misses Ground Contact, Causing One‑Orbit Delay in Weather Data

NOAA reports a brief delay in stored mission data from polar satellite NOAA‑20 after an April 6 ground contact miss; engineers expected recovery on a later pass.

#noaa, #weather, #satellites, #satelliteops