In the quest to extend human lifespan, tech billionaires like Sam Altman, Peter Thiel, and Jeff Bezos are investing heavily in biotechnology and artificial intelligence-driven solutions aimed at slowing or reversing aging. However, Dr. Eric Topol, founder of the Scripps Research Translational Institute, advocates for a more immediate and accessible approach: predicting and preventing chronic diseases.

In his new book, "Super Agers," released on May 6, 2025, Dr. Topol emphasizes that the key to longevity lies not in reversing aging but in leveraging scientific advances to prevent age-related diseases such as cancer, heart disease, and Alzheimer's. He notes that these conditions develop over decades, providing ample opportunities for early intervention.

"The answer doesn't lie in turning back time, but in harnessing our improved capabilities to predict and prevent chronic diseases," Dr. Topol writes. He highlights the potential of drugs like GLP-1s, known for their anti-inflammatory properties, in disease prevention. Additionally, he underscores the importance of understanding how lifestyle factors influence inflammation and immunity in promoting healthy aging.

While experimental age-reversing technologies show promise in animal studies, they come with significant safety and affordability concerns and may never work in humans. Dr. Topol suggests that the most impactful strategies for extending lifespan may lie in improved medical practices and lifestyle adjustments, not futuristic treatments reserved for the wealthy.

Policymakers are beginning to engage with longevity research. Recently, a group of researchers on aging met with House lawmakers and Centers for Medicare and Medicaid Services administrator Mehmet Oz on ... . However, some figures, such as Elon Musk, remain skeptical. Musk reportedly refused to invest in longevity ... .

Ultimately, Dr. Topol advocates for a shift in focus from experimental age-reversing technologies to practical strategies that can be implemented today. By emphasizing disease prevention and lifestyle modifications, he believes that significant strides can be made in promoting healthy aging and extending human lifespan.